First of all, it is clear that it does not need to be rubbed on the penis, but to wipe it on the upper arm and shoulder.
It is reported that clinical trials begin in April, and will last for four years, which will be the greatest efforts of the United States in regulating contraception on male hormones.
At present, male contraceptive methods are relatively simple, either condoms or vasectomy. From 2008 to 2012, Europe conducted a study on regulating hormonal hormones to help male contraception. Participants received hormonal injections every two months. These hormones inhibit the production of spermatozoa and achieve the effect of male contraception, but they also bring severe emotional fluctuations and other serious side effects to men.
The new gel contains two kinds of synthetic hormones, progestin and testosterone. Progestin prevents the testicles from producing enough testosterone to produce normal levels of sperm. Testosterone is mainly used to counteract the hormonal imbalance caused by progestin, but it does not induce the body to produce sperm.
More than 400 couples will take part in the research. The experiment will also be carried out in parts of the United States, Britain, Italy, Sweden, Chile and Kenya. The men involved in the experiment will take a bottle of condensing tape home and wipe half a spoon on the upper arm and shoulder every day. The gel will dry in a minute.
The men who participated in the experiment would continue to use the gel for at least four months, and their partners used some form of female contraception. According to Bridge, the researchers will monitor the sperm level in the male body and need to be reduced to less than 1 million per milliliter to effectively prevent pregnancy. Once the sperm number is low enough, their partner will give up the means of birth control. The couple will then use the Contraceptive Gel as their daily contraceptive method.
In the first six months of study, the method has been proved to be effective. But because of the two kinds of gel that must be applied to different parts of the body, Bridge's research team worked with the researchers of the population committee to reconstruct the hormone and combine it into a gel. She says the gel is better than the hormone pill, because the testosterone produced in the laboratory is quickly removed by the body. In the gel, the hormone is absorbed by the skin and is attached to the blood for longer.
But the question is: do men use it?
Historically, pharmaceutical companies have little interest in male contraceptives. It takes years to carry out clinical trials, and the price is very high, so it's a risky attempt when there are many women's contraceptive programs.
But as Sitruk-Ware and other researchers say, ideas are changing, and men, especially young men, are open to the use of contraceptives. "This is the idea of gender equality," she said. Men also want to be able to regulate their fertility, rather than being forced to be fathers. "
In addition, some women are unable to use hormonal contraception for medical reasons, so if there is another choice, it is good for those couples.
The attitude of men to contraception varies from region to region. But a 2010 survey showed that at least 25% of the men around the world would consider the use of the hormone contraceptive.
The biggest problem may be not a boycott, but a forgetfulness. In a small survey conducted in 2011 in Britain, 42% of respondents feared that men would forget to take contraceptives, and women were more worried. Forgetting to take drugs every day is the primary cause of the failure of the oral contraceptive. According to a recent study, the typical failure rate of these methods was 7%, while the contraceptive failure rate of condoms was 13%.